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Item number: Cay43733-1

IMG-7289 is an irreversible inhibitor of lysine-specific demethylase 1 (LSD1). It induces cell cycle arrest at the S phase in SET-2 acute megakaryoblastic leukemia cells and apoptosis in Ba/F3 murine hematopoietic cells expressing Jak2 containing a valine-to-phenylalanine substitution at position 617 (Jak2V617F)...

Keywords:	Bomedemstat ditosylate, N-[(1S)-4-[[(1R...
Application:	Irreversible LSD1 inhibitor
CAS	1990504-72-7
MW:	864 D

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Bomedemstat ditosylate

Item number: TGM-T70008-100mg

Description: Bomedemstat ditosylate (IMG-7289 ditosylate) is an orally active lysine-specific demethylase 1 (LSD1) inhibitor with antitumor activity that potentiates the response to PD-1 inhibition in a homozygous model of SCLC, inhibits cancer cell proliferation, and induces apoptosis. Bomedemstat ditosylate can be...

Keywords:	MK-3543 ditosylate, IMG-7289 ditosylate
Application:	Targets KDM1A (AOF2, LSD1)
CAS	1990504-72-7
MW:	864.02 D

From 110.00€ *

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