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Item number: Cay28441-10

Nicotinamide N-oxide is a metabolite of nicotinamide (Cay-11127). It is formed via oxidation of nicotinamide by the cytochrome P450 (CYP) isoform CYP2E1. Nicotinamide N-oxide (30 mM) inhibits proliferation and induces reduction of nitroblue tetrazolium (NBT, Cay-17341), indicating cell differentiation, in HL-60...

Keywords:	NSC 168416, NSC 30531, 3-pyridinecarboxamide, 1-oxide
Application:	CYP2E1 nicotinamide metabolite
CAS	1986-81-8
MW:	138.1 D

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Nicotinamide N-oxide

Item number: TGM-T0617-100mg

Description: Nicotinamide N-oxide (Nicotinamide 1-oxide) is recognized as an in vivo metabolite of nicotinamide which is a precurser of nicotinamide-adenine dinucleotide (NAD+) in animals. The enzyme that catalyzes the reduction of nicotinamide N-oxide to nicotinamide in the liver is xanthine oxidase. Target: Drug...

Keywords:	Nicotinamide 1-oxide, Nicotinamide-N-oxide, 1-oxynicotinamide
CAS	1986-81-8
MW:	138.12 D

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