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Baloxavir marboxil
Baloxavir marboxil

Item number: TGM-T6195-100mg

Description: Baloxavir marboxil (S-033188) is a novel cap-dependent endonuclease inhibitor designed for the treatment of influenza A and B virus infections. Target: Influenza Virus. Smiles: O(COC(OC)=O)C1=C2N(N([C@]3(N(C2=O)CCOC3)[H])[C@H]4C=5C(CSC=6C4=CC=CC6)=C(F)C(F)=CC5)C=CC1=O. References: Koszalka P , Tilmanis...
Keywords: S-033188
Application: Targets Influenza virus polymerase acidic protein (PA)
CAS 1985606-14-1
MW: 571.55 D
From 42.00€ *
Review
Baloxavir Marboxil
Baloxavir Marboxil

Item number: Cay33214-250

Baloxavir marboxil is a prodrug form of the antiviral and influenza virus cap-dependent endonuclease (CEN) inhibitor baloxavir acid. It inhibits influenza CEN and CEN/RNA-dependent RNA polymerase (CEN/RdRp) activity in cell-free assays (IC50s = 530 and 340 nM, respectively). Baloxavir marboxil prevents mortality in...
Keywords: BXM, S-033188,...
Application: Antiviral baloxavir acid prodrug
CAS 1985606-14-1
MW: 571.6 D
From 150.00€ *
Review
Baloxavir Marboxil
Baloxavir Marboxil

Item number: LKT-B011460.100

Baloxavir, and its prodrug baloxavir marboxil, is a cap-dependent endonuclease inhibitor, leading to inhibition of RNA transcription and replication. Baloxavir shows potent activity against two influenza A strains with noted synergistic effects when used in combination with oseltamivir. Baloxavir has also been...
Keywords: Xofluza, S-033188,...
Application: Antiviral, Cap-dependent endonuclease inhibitor, Prodrug
CAS 1985606-14-1
MW: 571.6 D
From 66.00€ *
Review