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Baloxavir
Item number: TGM-T14495-100mg
Description: Baloxavir (S-033447) is a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit. Target: Influenza Virus. Smiles: Oc1c2C(=O)N3CCOC[C@H]3N([C@@H]3c4ccccc4SCc4c(F)c(F)ccc34)n2ccc1=O. References: Omoto S, et al. Characterization of influenza virus variants induced...
| Keywords: | Baloxavir acid, S-033447 |
| Application: | Targets Influenza virus polymerase acidic protein (PA) |
| CAS | 1985605-59-1 |
| MW: | 483.49 D |
From 71.00€
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Baloxavir
Item number: LKT-B011458.1
Baloxavir, and its prodrug baloxavir marboxil, is a cap-dependent endonuclease inhibitor, leading to inhibition of RNA transcription and replication. Baloxavir shows potent activity against two influenza A strains with noted synergistic effects when used in combination with oseltamivir. Baloxavir has also been...
| Keywords: | Baloxavir acid, 4G86Y4JT3F,... |
| Application: | Antiviral, Cap-dependent endonuclease inhibitor |
| CAS | 1985605-59-1 |
| MW: | 483.5 D |
From 66.00€
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Baloxavir
Item number: Cay35125-100
Baloxavir is an active metabolite of baloxavir marboxil (Cay-33214). It inhibits influenza virus cap-dependent endonuclease (CEN) and CEN/RNA-dependent RNA polymerase (CEN/RdRp) activities in cell-free assays (IC50s = 2.5 and 1.6 nM, respectively). Baloxavir reduces viral titers in MDCK cells infected with...
| Keywords: | BXA, S-033447,... |
| Application: | Baloxavir marboxil active metabolite |
| CAS | 1985605-59-1 |
| MW: | 483.5 D |
From 44.00€
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