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GB1107
Item number: Cay34584-1
A Gal-3 inhibitor (IC50 = 8 µM), prevents GPN-induced increases in Gal-3 levels in JIMT-1 cells (IC50 = 36 nM), induces apoptosis, induces cell cycle arrest at the G1 phase, and decreases the levels of aggrecan, Ccl3, and Mmp-3 in primary rat cartilage end plate cells at 25 µM, increases survival and decreases...
| Keywords: | 3,4-dichlorophenyl 3-deoxy-1-thio-3-[4-(3,4,5-trifluorophenyl)-1H-1,2,3-triazol-1-yl]-alpha-D-galactopyranoside |
| Application: | Galectin-3 inhibitor |
| CAS | 1978336-61-6 |
| MW: | 522.33 D |
From 88.00€
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GB1107
Item number: TGM-T15372-10mg
Description: GB1107 is an effective and selective Galectin-3 inhibitor with a Kd of 37 nM. Target: Galectin. Smiles: OC[C@H]1O[C@H](Sc2ccc(Cl)c(Cl)c2)[C@H](O)[C@H]([C@H]1O)n1cc(nn1)-c1cc(F)c(F)c(F)c1. References: Vuong L, et al. An orally active galectin-3 antagonist inhibits lung adenocarcinoma growth and augments...
| Keywords: | (2R,3R,4S,5R,6R)-2-(3,4-dichlorophenyl)sulfanyl-6-(hydroxymethyl)-4-[4-(3,4,5-trifluorophenyl)triazol-1-yl]oxane-3,5-diol |
| CAS | 1978336-61-6 |
| MW: | 522.32 D |
From 53.00€
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