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LDH-IN-1
LDH-IN-1

Item number: Cay44281-1

LDH-IN-1 is an inhibitor of lactate dehydrogenase A (LDHA) and LDHB (IC50s = 0. and 0. µM, respectively). It is selective for LDHA and LDHB over malate dehydrogenase (MDH) and isocitrate dehydrogenase 1 (IDH1, IC50s = 37. and 29. µM, respectively). LDH-IN-1 is cytotoxic to A-673 sarcoma and MiaPaCa-2 pancreatic...
Keywords: Lactate Dehydrogenase Inhibitor 1, Lactate Dehydrogenase-IN-1, LDH Inhibitor 1
Application: LDHA / LDHB inhibitor
CAS 1964515-43-2
MW: 570.68 D
From 112.00€ *
Review
LDH-IN-1
LDH-IN-1

Item number: TGM-T11829-100mg

Description: LDH-IN-1 is a pyrazole-based human lactate dehydrogenase (LDH) inhibitor(IC50s of 32 and 27 nM for LDHA and LDHB, respectively). Target: Dehydrogenase. Smiles: NS(=O)(=O)c1ccc(Cc2c(CC3CC3)n(nc2-c2cccc(c2)-c2ccccc2)-c2nc(cs2)C(O)=O)cc1. References: Rai G, et al. Discovery and Optimization of Potent,...
CAS 1964515-43-2
MW: 570.68 D
From 187.00€ *
Review