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Item number: Cay14795-5

In the classical pathway of NF-kappaB activation, phosphorylation of the inhibitor of NF-kappaB (IkappaBalpha) releases the inhibitor from NF-kappaB, allowing IkappaBalpha degradation and NF-kappaB activation and nuclear import. BAY 11-7085 is an irreversible inhibitor of IkappaBalpha phosphorylation, preventing...

Keywords:	3-[[4-(1,1-dimethylethyl)phenyl]sulfonyl]-2E-propenenitrile
Application:	Irreversible IkappaBalpha phosphorylation inhibitor
CAS	196309-76-9
MW:	249.3 D

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