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BGC-20-1531 hydrochloride(1186532-61-5 free base)
BGC-20-1531 hydrochloride(1186532-61-5 free base)

Item number: TGM-T8993L-10mg

Description: BGC-20-1531 hydrochloride(1186532-61-5 free base) (GTPL3380 hydrochloride) is a EP4 antagonist for the treatment of acute migraine. Target: Prostaglandin Receptor. Smiles: CC1=CC=CC=C1S(=O)(=O)NC(=O)C2=CC(=C(O2)C)COC3=CC=C(C=C3)C4=NC=C(C=C4)OC.Cl. References: Czigler A , Toth L , Szarka N , et al....
Keywords: GTPL3380 hydrochloride, BGC-20-1531 hydrochloride, AP-1531 hydrochloride
Application: EP4 antagonist
CAS 1962928-26-2
MW: 529 D
From 133.00€ *
Review
BGC 20-1531 (hydrochloride)
BGC 20-1531 (hydrochloride)

Item number: Cay19742-1

BGC 20-1531 is a potent and selective antagonist of the prostaglandin E2 (PGE2, Cay-14010) receptor subtype 4 (EP4) with Ki values of 11.7, >10,000, and >10,000 nM for EP4, EP2, and EP3, respectively. It is selective for EP4, exhibiting 2-induced cAMP accumulation in a dose-dependent manner in HEK293 EBNA cells that...
Keywords: PGN 1531, 4-[[4-(5-methoxy-2-pyridinyl)phenoxy]methyl]-5-methyl-N-[(2-methylphenyl)sulfonyl]-2-furancarboxamide,...
Application: EP4 antagonist
CAS 1962928-26-2
MW: 529 D
From 44.00€ *
Review