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Item number: TGM-T6868-100mg

Description: KYA1797K is a highly potent and selective inhibitor. Wnt/beta-catenin IC50 is 0.75 µM through TOPflash assay. Target: Wnt/beta-catenin. Smiles: [K+].[O-]C(=O)CCN1C(=S)S\C(=C/c2ccc(o2)-c2ccc(cc2)[N+]([O-])=O)C1=O. References: Cha PH, et al. Nat Chem Biol. 2016, 12(8):593-600.

Application:	Wnt/beta-catenin signaling inhibitor
CAS	1956356-56-1
MW:	442.51 D

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KYA1797K

Item number: Cay29221-10

KYA1797K is an inhibitor of Wnt/beta-catenin signaling. It inhibits expression of a reporter induced by Wnt3a-conditioned medium in HEK293 cells (IC50 = 0.75 µM). KYA1797K binds to the regulators of G-protein signaling (RGS) domain of axin and increases activation of GSK3beta, as well as phosphorylation of...

Keywords:	(5Z)-5-[[5-(4-nitrophenyl)-2-furanyl]methylene]-4-oxo-2-thioxo-3-thiazolidinepropanoic acid, monopotassium salt
Application:	Wnt/beta-catenin signaling inhibitor
CAS	1956356-56-1
MW:	442.5 D

From 111.00€ *

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