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(Z)-Semaxinib
(Z)-Semaxinib

Item number: TGM-T2496-100mg

Description: (Z)-Semaxinib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor (IC50: 1.23 µM), 20-fold more selective for VEGFR over PDGFRbeta, no inhibition for FGFR, InsR, and EGFR. (Z)-Semaxinib is a quinolone derivative with potential antineoplastic activity. Target: VEGFR. Smiles:...
Keywords: SU5416
Application: Targets fms-related tyrosine kinase 3 [EC:2.7.10.1] (FLT3, FLK2, CD135)
CAS 194413-58-6
MW: 238.28 D
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