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MP07-66
MP07-66

Item number: Cay42337-1

An inhibitor of the SET-PP2A protein-protein interaction, increases PP2A activity in isolated human B-CLL cells at 3 and 8 µM, does not decrease plasma membrane S1P1 levels in isolated human B-CLL cells at 8 µM, induces apoptosis in isolated human B-CLL cells when used alone or in combination with dasatinib....
Keywords: N-(2,2-diethoxyethyl)-4-(hexyloxy)-benzenemethanamine
Application: SET (I2PP2A)-PP2A protein-protein interaction inhibitor
CAS 1938056-90-6
MW: 323.47 D
From 73.00€ *
Review
MP07-66
MP07-66

Item number: TGM-T9744-100mg

Description: MP07-66 is a novel FTY720-analog devoid of immunosuppressive effects leads to the reactivation of PP2A, which in turn triggers apoptosis of CLL cells. Target: Phosphatase. Smiles: CCCCCCOc1ccc(CNCC(OCC)OCC)cc1. References: Zonta F, et al. Lyn sustains oncogenic signaling in chronic lymphocytic leukemia...
CAS 1938056-90-6
MW: 323.47 D
From 37.00€ *
Review