Description: Direct Black 38 is an azo dye.It induces unscheduled DNA synthesis in liver and micronucleus in bone marrow of rats in vivo[1]. Target: Others. Smiles: O=S(O)(C1=CC2=CC(S(=O)(O)=O)=C(C(N)=C2C(O)=C1N=NC3=CC=CC=C3)N=NC4=CC=C(C5=CC=C(N=NC6=CC=C(C=C6N)N)C=C5)C=C4)=O.[Na].[Na]. References: Beije B. Induction...

Ferristatin II is an inhibitor of iron uptake. It inhibits iron uptake (IC50 = ~12 µM), as well as induces degradation of transferrin receptor protein 1 (TfR1), an effect that can be reversed by the lipid membrane disruptor nystatin, in HeLa cells. In vivo ferristatin II (0.2, 10, and 40 mg/kg) reduces serum iron...