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DDR-TRK-1
Item number: Cay41321-1
DDR-TRK-1 is an inhibitor of discoidin domain receptor 1 (DDR1, IC50 = 9.4 nM). It is selective for DDR1 over DDR2 and Abl1 (IC50s = 188 and >10,000 nM, respectively) and 461 additional kinases at 1 µM but does inhibit cyclin-dependent kinase 11 (Cdk11), ephrin type-A receptor 8 (EPHA8), muscle-associated receptor...
| Keywords: | Discoidin Domain Receptor-TRK-1,... |
| Application: | DDR1 inhibitor |
| CAS | 1934246-19-1 |
| MW: | 492.5 D |
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DDR-TRK-1
Item number: TGM-T10984-100mg
Description: DDR-TRK-1, a selective discoid domain receptor 1 (DDR1) inhibitor, exhibits an IC50 value of 9.4 nM and also inhibits the TRK family. Target: Discoidin Domain Receptor (DDR). Smiles: C[C@@H]1C=2C(CN(C1)C=3C=NC=NC3)=CC(C(NC4=CC(=CC(C(F)(F)F)=C4)N5C=NC(C)=C5)=O)=CC2. References: Zhen Wang, et al....
| CAS | 1934246-19-1 |
| MW: | 492.5 D |
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