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Item number: Cay43192-10

Co 101244 is an antagonist of NR1A/2B subunit-containing NMDA receptors (IC50 = 0. µM). It is selective for NR1A/2B subunit-containing NMDA receptors over NR1A/2A and NR1A/2C subunit-containing NMDA receptors (IC50s = >100 µM for both). In vivo, Co 101244 reduces the number of seizures induced by maximum...

Keywords:	PD 174494, 1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-methylphenyl)methyl]-4-piperidinol, monohydrochloride
Application:	NR1A/2B subunit-containing NMDA receptor antagonist
CAS	193356-17-1
MW:	377.91 D

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