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Item number: Cay21771-10

C527 is an inhibitor of USP1/UAF complex deubiquitinase activity (IC50 = 0.88 µM). It also inhibits USP5, UCL-H3, and USP12/46 but not UCL-H1 activity (IC50s = 1.65, 2.18, 5.97, and >10 µM, respectively). C527 increases ubiquinated Fanconi anemia complementation group D2 (FANCD2-Ub) and FANCI-Ub levels in a...

Keywords:	2-(4-fluorophenyl)-naphth[2,3-d]oxazole-4,9-dione
Application:	USP1/UAF complex deubiquitinase inhibitor
CAS	192718-06-2
MW:	293.3 D

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