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NCT-503
Item number: TGM-T4213-100mg
Description: NCT-503 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells. Target: FLT, Dehydrogenase, TAM Receptor. Smiles: Cc1cc(C)nc(NC(=S)N2CCN(Cc3ccc(cc3)C(F)(F)F)CC2)c1. References: Pacold ME, et al. A PHGDH inhibitor reveals coordination...
| Keywords: | NCT 503 |
| Application: | PHGDH inhibitor |
| CAS | 1916571-90-8 |
| MW: | 408.48 D |
From 37.00€
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NCT-503
Item number: Cay19718-5
NCT-503 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells with an IC50 value of 2.5 µM. It has been shown to reduce the production of glucose-derived serine in cells and to suppress the growth of PHGDH-dependent MDA-MB-468 cancer cells both in...
| Keywords: | N-(4,6-dimethyl-2-pyridinyl)-4-[[4-(trifluoromethyl)phenyl]methyl]-1-piperazinecarbothioamide |
| Application: | PHGDH inhibitor |
| CAS | 1916571-90-8 |
| MW: | 408.5 D |
From 44.00€
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