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Item number: Cay32737-1

Danicopan is an inhibitor of Factor D, a protease in the alternative complement pathway (APC, IC50 = 15 nM in a cell-free assay). It is selective for Factor D over a panel of 12 serine proteases when used at a concentration of 10 µM. Danicopan inhibits hemolysis of erythrocytes isolated from patients with paroxysmal...

Keywords:	ACH-4471,...
Application:	Factor D inhibitor
CAS	1903768-17-1
MW:	580.4 D

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Danicopan

Item number: TGM-T8509-100mg

Description: Danicopan (ACH-4471) (ACH-4471) is a selective, orally active small molecule factor D inhibitor with high binding affinity to human factor D, with a Kd value of 0.54 nM. Danicopan (ACH-4471) inhibits the activity of the complement replacement pathway (APC) and may block the complement replacement...

Keywords:	ACH-4471
Application:	Targets complement factor D [EC:3.4.21.46] (CFD)
CAS	1903768-17-1
MW:	580.41 D

From 91.00€ *

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