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Item number: Cay45283-1

A potassium-competitive acid blocker, increases TEER and occludin and Muc-1 levels at 20 µg/ml in a Caco-2 cell model of DSS-induced UC, reduces ileal levels of TNF-alpha, IL-6, and IL-1beta in a mouse model of IDM-induced small intestinal injury at 20 mg/kg. SMILES:...

Keywords:	DWP14012, Fexuprazan, 5-(2,4-difluorophenyl)-1-[(3-fluoro phenyl)sulfonyl]-4-methoxy-N-methyl-1H-pyrrole-3-methanamine
Application:	Potassium-competitive acid blocker (P-CAB)
CAS	1902954-60-2
MW:	410.41 D

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Abeprazan

Item number: TGM-T10221L-100mg

Description: Abeprazan (DWP14012) is a potassium-competitive acid blocker developed as a potential alternative to proton pump inhibitors for treating acid-related diseases. It inhibits H+, K+-ATPase through reversible potassium-competitive ionic binding, without requiring acid activation [1]. Target: Others. Smiles:...

Keywords:	DWP14012
CAS	1902954-60-2
MW:	410.41 D

From 821.00€ *

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