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Ophiobolin C
Ophiobolin C

Item number: Cay20186-1

Ophiobolin C is a sesterterpenoid fungal phytoxin produced by many species of the genus Bipolaris. It has been identified as an antagonist of chemokine receptor CCR5 binding (IC50 = 40 µM) to the envelope protein gp120 and to CD4, which is known to mediate HIV-1 viral entry into cells. Ophiobolin C is also reported...
Keywords: (1R,3aS,6aS,7R,9aR,10aS)-7-[(1S)-1,5-dimethyl-4-hexen-1-yl]-1,2,3,3a,6,6a,7,8,9,9a,10,10a-dodecahydro-1-hydroxy-1,9a-dimet...
Application: CCR5 to gp120 / CD4 binding antagonist
CAS 19022-51-6
MW: 386.6 D
From 426.00€ *
Review
Ophiobolin C
Ophiobolin C

Item number: TGM-T23108-1mg

Description: inhibitor of human CCR5 binding to HIV-1 gp120. Target: Others. Smiles: [H][C@@]1(CC[C@]2(C)C[C@@]3([H])[C@]([H])(C(=O)C[C@@]3(C)O)\C(C=O)=C/C[C@@]12[H])[C@@H](C)CCC=C(C)C
Application: CCR5 to gp120 / CD4 binding antagonist
CAS 19022-51-6
MW: 386.57 D
From 657.00€ *
Review
Ophiobolin C (Zizzanin A)
Ophiobolin C (Zizzanin A)

Item number: O7024-02.1

Ophiobolin C is a member of the ophiobolin class of phytotoxic metabolites produced by many species of the genus Bipolaris. Ophiobolin C is an inhibitor of human CCR5 binding to the envelope protein gp120 and CD4 that mediates HIV-1 viral entry into cells. Blockade of this binding was considered by scientists at...
CAS 19022-51-6
MW: 386,6 D
715.00€ *
Review