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Item number: Cay37689-1

GK241 is a secretory phospholipase A2 (sPLA2) (Type IIA) inhibitor (IC50s = 0.143 and 0.068 µM for the human and mouse enzymes, respectively). It inhibits IL-1beta-induced production of prostaglandin E2 (PGE2, Cay-14010) in isolated rat renal mesangial cells when used at concentrations of 3 and 10 µM. GK241 also...

Keywords:	N-(1,2-dioxohexadecyl)-L-valine
Application:	sPLA2 (type IIA) inhibitor
CAS	1899930-93-8
MW:	369.5 D

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