A colorimetric substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase.

Description: Ac-DEVD-pNA is the preferred peptidic substrate for caspase-3. Target: Caspase, Others. Smiles: CC(C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(C)=O)C(=O)N([C@@H](CC(N)=O)C(O)=O)c1ccc(cc1)[N+]([O-])=O. References: Talanian RV, et al. Substrate specificities of caspase family proteases. J Biol...