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BAY-1816032
Item number: TGM-T10467-100mg
Description: BAY-1816032 is a potent and orally available inhibitor of BUB1 kinase (IC50: 7 nM). Target: Others. Smiles: COc1cnccc1Nc1nc(ncc1OC)-c1nn(Cc2c(F)cc(OCCO)cc2F)c2ccccc12. References: Siemeister G, et al. BAY 1816032, a novel BUB1 kinase inhibitor with potent antitumor activity [abstract]. In: Proceedings...
| CAS | 1891087-61-8 |
| MW: | 534.51 D |
From 33.00€
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BAY-1816032
Item number: LKT-B030964.1
BUB1 inhibitor.
| Keywords: | BAY 1816032, BAY1816032 |
| Application: | BUB1 inhibitor |
| CAS | 1891087-61-8 |
| MW: | 534.52 D |
From 142.00€
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BAY-1816032
Item number: Cay35095-1
BAY-1816032 is an inhibitor of the mitotic checkpoint serine/threonine protein kinase BUB1 (IC50 = 6.1 nM). It is selective for BUB1 over FLT3 (IC50 = 4.2 µM) and 15 other kinases (IC50s = >10 µM for all). BAY-1816032 inhibits proliferation of a variety of cancer cells (median IC50 = 1.4 µM) and acts synergistically...
| Keywords: | 2-[3,5-difluoro-4-[[3-[5-methoxy-4-[(3-methoxy-4-pyridinyl)amino]-2-pyrimidinyl]-1H-indazol-1-yl]methyl]phenoxy]-ethanol |
| Application: | BUB1 kinase inhibitor |
| CAS | 1891087-61-8 |
| MW: | 534.5 D |
From 61.00€
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