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Item number: Cay16402-10

Tetrahydrouridine is an inhibitor of cytidine deaminase (Kis = 54 and 240 nM for the human and E. coli enzymes, respectively). In vivo, tetrahydrouridine inhibits the metabolism of decitabine (Cay-11166) and enhances decitabine-induced inhibition of tumor growth in a B16 murine melanoma model.Formal Name:...

Keywords:	NSC 112907, THU, 3,4,5,6-tetrahydro-uridine
Application:	Competitive, reversible cytidine deaminase inhibitor
CAS	18771-50-1
MW:	248.2 D

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