3 products were found matching "1874276-76-2"!

No results were found for the filter!
LXS-196
LXS-196

Item number: Cay31455-5

LXS-196 is a PKC inhibitor (IC50s = 1.9 and 0.4 nM for PKCalpha and PKCtheta, respectively). It is selective for PKCalpha and PKCtheta over GSK3beta (IC50 = 3,100 nM). It inhibits proliferation of TMD8 B cell lymphoma and 92.1 uveal melanoma cells (IC50s = 900 and 184 nM, respectively) but not SK-MEL-28 skin...
Keywords: 3-amino-N-[3-(4-amino-4-methyl-1-piperidinyl)-2-pyridinyl]-6-[3-(trifluoromethyl)-2-pyridinyl]-2-pyrazinecarboxamide
Application: PKC inhibitor
CAS 1874276-76-2
MW: 472.5 D
From 75.00€ *
Review
LXS-196
LXS-196

Item number: LKT-L943721.1

Selective inhibitor of protein kinase C (PKC).
Keywords: LXS 196, LXS196, NVP-LXS196
Application: Selective PKC inhibitor
CAS 1874276-76-2
MW: 472.48 D
From 123.00€ *
Review
Darovasertib
Darovasertib

Item number: TGM-T5600-100mg

Description: Darovasertib (LXS196) is a potent, selective, and orally active protein kinase C (PKC) inhibitor with IC50 values of 1.9 nM for PKCalpha, 0.4 nM for PKCtheta, and 3.1 µM for GSK3beta. Target: PKC. Smiles: CC1(N)CCN(CC1)c1cccnc1NC(=O)c1nc(cnc1N)-c1ncccc1C(F)(F)F. References: Shoushtari A N , Shoushtari A...
Keywords: LXS196
Application: Antineoplastic
CAS 1874276-76-2
MW: 472.47 D
From 46.00€ *
Review