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Item number: Cay43111-10

XY-018 is an inverse agonist of retinoic acid receptor-related orphan receptor gamma (RORgamma). It induces RORgamma transcriptional activity in a reporter assay using LNCaP cells (IC50 = 0. µM). XY-018 selectively induces RORgamma transcriptional activity over RORalpha transcriptional activity in HEK293T cells...

Keywords:	N-[2'-fluoro-4'-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl][1,1'-biphenyl]-4-yl]-2-nitro-benzeneacetamide
Application:	ROR gamma inverse agonist
CAS	1873358-87-2
MW:	516.37 D

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