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XY-018
XY-018

Item number: Cay43111-10

XY-018 is an inverse agonist of retinoic acid receptor-related orphan receptor gamma (RORgamma). It induces RORgamma transcriptional activity in a reporter assay using LNCaP cells (IC50 = 0. µM). XY-018 selectively induces RORgamma transcriptional activity over RORalpha transcriptional activity in HEK293T cells...
Keywords: N-[2'-fluoro-4'-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl][1,1'-biphenyl]-4-yl]-2-nitro-benzeneacetamide
Application: ROR gamma inverse agonist
CAS 1873358-87-2
MW: 516.37 D
From 151.00€ *
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XY018
XY018

Item number: TGM-T24213-2mg

Description: XY 018 is a RORgamma antagonist. It also suppresses androgen receptor expression in prostate cancer cell lines and inhibits the growth of tumors in androgen receptor-positive xenograft models. Target: Others. Smiles: OC(c1ccc(c(F)c1)-c1ccc(NC(=O)Cc2ccccc2[N+]([O-])=O)cc1)(C(F)(F)F)C(F)(F)F. References:...
Keywords: XY 018, XY-018
CAS 1873358-87-2
MW: 516.36 D
52.00€ *
Review