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GSK-3beta inhibitor 1
Item number: TGM-T11467-100mg
Description: GSK-3beta inhibitor 1 is an inhibitor of GSK-3beta( IC50 of 4.9 nM) and demonstrates high antidiabetic efficacy. Target: GSK-3. Smiles: C(=C\1/C=2C(NC1=O)=CC=CC2)\C3=CC=CC=N3. References: Lozinskaya NA, et al. Synthesis and biological evaluation of 3-substituted 2-oxindole derivatives as new glycogen...
| Application: | GSK-3beta inhibitor |
| CAS | 187325-53-7 |
| MW: | 222.24 D |
From 55.00€
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GSK3beta Inhibitor 1
Item number: Cay42107-10
A GSK3beta inhibitor (IC50 = 4.19 nM), decreases blood glucose levels in an OGTT in a rat model of high-fat diet and STZ-induced diabetes at 50 mg/kg. Formulation: A solid. InChI: InChI=1S/C14H10N2O/c17-14-12(9-10-5-3-4-8-15-10)11-6-1-2-7-13(11)16-14/h1-9H,(H,16,17)/b12-9-. InChIKey: YKQONSWBHGBDSB-XFXZXTDPSA-N....
| Keywords: | Glycogen Synthase Kinase 3beta Inhibitor I, (3Z)-1,3-dihydro-3-(2-pyridinylmethylene)-2H-indol-2-one |
| Application: | GSK3beta inhibitor |
| CAS | 187325-53-7 |
| MW: | 222.2 D |
From 223.00€
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