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Item number: TGM-T5538-100mg

Description: DC661 is a palmitoyl-protein thioesterase 1 (PPT1) inhibitor that acts as an anti-lysosomal agent by inhibiting autophagy, demonstrating anti-cancer activity. Target: Apoptosis, Autophagy. Smiles: CN(CCCCCCNc1ccnc2cc(Cl)ccc12)CCCCCCNc1ccnc2cc(Cl)ccc12. References: Rebecca VW, et al. PPT1 Promotes Tumor...

Application:	PPT1 inhibitor
CAS	1872387-43-3
MW:	552.58 D

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DC661

Item number: Cay34899-25

DC661 is an inhibitor of palmitoyl-protein thioesterase 1 (PPT1) and a dimeric form of hydroxychloroquine (Cay-17911). It binds to PPT1 and inhibits PPT1 enzyme activity in A375 cells when used at concentrations of 5, 10, and 100 µM. DC661 (10 µM) inhibits autophagic flux and induces apoptosis in B-RAF mutant...

Keywords:	N6-(7-chloro-4-quinolinyl)-N1-[6-[(7-chloro-4-quinolinyl)amino]hexyl]-N1-methyl-1,6-hexanediamine
Application:	PPT1 inhibitor
CAS	1872387-43-3
MW:	552.6 D

From 149.00€ *

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