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Pretomanid
Pretomanid

Item number: TGM-T6096-100mg

Description: Pretomanid ((S)-PA 824) , a nitroimidazole, is used as an anti-tuberculosis drug for tuberculosis with MIC less than 2.8 µM. Target: Antibiotic, Antibacterial. Smiles: [O-][N+](=O)c1cn2C[C@@H](COc2n1)OCc1ccc(OC(F)(F)F)cc1. References: Lenaerts AJ, et al. Antimicrob Agents Chemother. 2005, 49(6),...
Keywords: PA-824, (S)-PA 824
Application: Antibacterial (tuberculostatic)
CAS 187235-37-6
MW: 359.26 D
From 42.00€ *
Review
PA-824
PA-824

Item number: Cay13142-1

PA-824 is an anti-tuberculosis (anti-TB) agent that is activated intracellularly via deazaflavin-dependent nitroreductase (Ddn) metabolism into a desnitro metabolite that kills M. tuberculosis by releasing reactive nitrogen species (RNS), including nitric oxide. It is active against replicating and non-replicating...
Keywords: (S)-PA-824, (6S)-6,7-dihydro-2-nitro-6-[[4-(trifluoromethoxy)phenyl]methoxy]-5H-imidazo[2,1-b][1,3]oxazine
Application: Antibacterial antibiotic (tuberculostatic)
CAS 187235-37-6
MW: 359.3 D
From 52.00€ *
Review