3 products were found matching "186611-52-9"!

No results were found for the filter!
IC261
IC261

Item number: LKT-I0801.25

Casein kinase 1 inhibitor.
Keywords: SU5607, (3E)-3-(2,4,6-Trimethoxybenzylidene)-1,3-dihydro-2H-indol-2-one
Application: Casein kinase 1 inhibitor
CAS 186611-52-9
MW: 311.12 D
From 261.00€ *
Review
IC261
IC261

Item number: Cay17260-1

IC261 is a reversible, ATP-competitive inhibitor of casein kinase 1 (CK1) that inhibits CK1delta and CK1? (IC50 = ~1 µM for both), as well as CK1alpha (IC50 = 16 µM). It is at least 100-fold less effective against PKA, p34cdc2, and p55fyn. IC 261, at 1 µM, inhibits cytokinesis in primary mouse embryo fibroblasts....
Keywords: SU5607, 1,3-dihydro-3-[(2,4,6-trimethoxyphenyl)methylene]-2H-indol-2-one
Application: Casein kinase 1 delta / epsilon inhibitor
CAS 186611-52-9
MW: 311.3 D
From 51.00€ *
Review
IC261
IC261

Item number: TGM-T2440-100mg

Description: IC261 (SU-5607) is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50 of IC261 for CK1 was 16 µM and for Cdk5 is 4.5 mM. Target: Apoptosis, CDK, Casein Kinase. Smiles: COc1cc(OC)c(\C=C2\C(=O)Nc3ccccc23)c(OC)c1. References: Behrend L, et al. Oncogene. 2000, 19(47):5303-5313.
Keywords: SU-5607
CAS 186611-52-9
MW: 311.33 D
From 60.00€ *
Review