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Item number: Cay39156-1

CP 346,086 is an inhibitor of microsomal triglyceride transfer protein (MTTP, IC50 = 2 nM). It inhibits apolipoprotein B (ApoB) and triglyceride secretion in HepG2 cells (IC50 = 2.6 nM for both). CP 346,086 (10 mg/kg) lowers plasma triglyceride levels, as well as plasma total, VLDL, and LDL cholesterol levels in...

Keywords:	N-[1,2,3,4-tetrahydro-2-(1H-1,2,4-triazol-5-ylmethyl)-6-isoquinolinyl]-4'-(trifluoromethyl)- [1,1'-biphenyl]-2-carboxamide
Application:	MTTP (microsomal triglyceride transfer protein) inhibitor
CAS	186390-48-7
MW:	477.5 D

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