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ROC-325
Item number: TGM-T16777-100mg
Description: ROC-325 is an effective and orally active inhibitor of autophagy with anticancer activity. ROC-325 induces renal cell carcinoma apoptosis and exhibits favorable selectivity. Target: Apoptosis, Autophagy. Smiles: CN(CCNc1ccnc2cc(Cl)ccc12)CCNc1ccc(C)c2sc3ccccc3c(=O)c12. References: Carew JS, et al....
| CAS | 1859141-26-6 |
| MW: | 503.06 D |
From 31.00€
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ROC-325
Item number: Cay33566-1
ROC-325 is an autophagy inhibitor. It inhibits autophagic flux and induces lysosomal deacidification and apoptosis in 786-O renal cell carcinoma cells when used at a concentration of 5 µM. ROC-325 decreases viability in a panel of 12 cancer cell lines, including renal, lung, pancreatic, and prostate cancer cells,...
| Keywords: | 1-[[2-[[2-[(7-chloro-4-quinolinyl)amino]ethyl]methylamino]ethyl]amino]-4-methyl-9H-thioxanthen-9-one |
| Application: | Autophagy inhibitor |
| CAS | 1859141-26-6 |
| MW: | 503.1 D |
From 52.00€
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