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Item number: Cay32741-1

TAK-981 is an inhibitor of SUMO-activating enzyme (SAE, IC50 = in vitro. TAK-981 upregulates the expression of IFN-regulated genes in the blood and tumor tissue in an A20 syngeneic lymphoma mouse model. It also decreases intratumor levels of SUMOlyated proteins and reduces tumor growth in the same model.Formal Name:...

Keywords:	[(1R,2S,4R)-4-[[5-[[4-[(1R)-7-chloro-1,2,3,4-tetrahydro-1-isoquinolinyl]-5-methyl-2-thienyl]carbonyl]-4-pyrimidinyl]amino]...
Application:	SUMO-activating enzyme (SAE) inhibitor
CAS	1858276-04-6
MW:	578.1 D

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