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Tomivosertib
Item number: TGM-T3468-100mg
Description: Tomivosertib (eFT508) is a potent and highly selective MNK1 and MNK2 inhibitor with an IC50 value of 1-2 nM. Target: PD-1/PD-L1, MNK. Smiles: Cc1cc(Nc2cc(N)ncn2)c(=O)n2c1C(=O)NC21CCCCC1. References: Kevin R Webster, et al. eFT508, a Potent and Selective Mitogen-Activated Protein Kinase Interacting...
| Keywords: | eFT508 |
| Application: | Targets MAP kinase interacting serine/threonine kinase [EC:2.7.11.1] (MKNK, MNK) |
| CAS | 1849590-01-7 |
| MW: | 340.38 D |
From 60.00€
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eFT508
Item number: Cay21957-5
eFT508 is a potent inhibitor of MAPK interacting protein kinases (MNK) 1 and 2 (IC50s = 50 value of 98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 0.5 mg/ml, DMSO: 1 mg/ml. lambdamax: 237, 357 nm. SMILES: NC1=NC=NC(NC2=CC(C)=C(C(NC34CCCCC4)=O)N3C2=O)=C1. InChi Code:...
| Keywords: | 6'-[(6-amino-4-pyrimidinyl)amino]-8'-methyl-spiro[cyclohexane-1,3'(2'H)-imidazo[1,5-a]pyridine]-1',5'-dione |
| CAS | 1849590-01-7 |
| MW: | 340.4 D |
From 66.00€
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