- Search results for 184475-35-2
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6 products were found matching "184475-35-2"!
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Item number: Cay13166-250
Gefitinib is an EGFR inhibitor (IC50s = 0.023-0.079 µM). It inhibits colony formation of GEO colon, ZR-75-1 and MCF-10A breast, and OVCAR-3 ovarian cancer cell lines in soft agar assays (IC50s = 0.2-0.4 µM). Gefitinib (0.1 to 1 µM) induces apoptosis and inhibits EGFR autophosphorylation in the same cells. In vivo,...
Keywords: | ZD 1839, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine |
Application: | EGFR-TK inhibitor |
CAS | 184475-35-2 |
MW: | 446.9 D |
From 100.00€
*
Item number: SYN-1042-M001
Soluble in DMSO or ethanol. Gefitinib is a selective, orally available epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor. In NR6wtEGFR and NR6W cells, it inhibits Tyr1173, Tyr992, Tyr1173 and Tyr992 with IC(50) values of 37nM, 37nM, 26nM and 57nM, respectively. Target: EGFR , Kinase Group: RTK ,...
Keywords: | ZD1839, Iressa |
Application: | EGFR inhibitor |
CAS | 184475-35-2 |
MW: | 446,9 D |
From 53.00€
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Item number: LC-G-4408_1g
Soluble in DMSO, up to about 100 mg/mL, very poorly soluble in water or ethanol
Keywords: | ZD 1839, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine |
Application: | EGFR-TK inhibitor |
CAS | 184475-35-2 |
MW: | 446,9 D |
From 99.00€
*
Item number: G2023-95A.1
EGFR tyrosine kinase inhibitor that binds to the ATP-binding site of the enzyme. The functions of the EGFR tyrosine kinase in activating the Ras signal transduction cascade and malignant cell growth are thus inhibited. It has been shown that a mutation in the EGFR tyrosine kinase domain is responsible for activating...
CAS | 184475-35-2 |
MW: | 446.90 |
308.00€
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Item number: Cay13166-100
Gefitinib is an EGFR inhibitor (IC50s = 0.023-0.079 µM). It inhibits colony formation of GEO colon, ZR-75-1 and MCF-10A breast, and OVCAR-3 ovarian cancer cell lines in soft agar assays (IC50s = 0.2-0.4 µM). Gefitinib (0.1 to 1 µM) induces apoptosis and inhibits EGFR autophosphorylation in the same cells. In vivo,...
Keywords: | ZD 1839, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine |
Application: | EGFR-TK inhibitor |
CAS | 184475-35-2 |
MW: | 446.9 D |
44.00€
*