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Item number: Cay34362-10

CPPG is an antagonist of group II and group III metabotropic glutamate receptors (mGluRs). It reverses inhibition of forskolin-induced cAMP accumulation induced by the mGluR group II selective agonist L-CCG-1 or the mGluR group III-selective agonist L-AP4 (Cay-14538) in rat cerebrocortical slices (IC50s = 46.2 and...

Keywords:	alpha-Cyclopropyl-4-phosphonophenylglycine, alpha-amino-alpha-cyclopropyl-4-phosphono-benzeneacetic acid
Application:	Group II and group III mGluR antagonist
CAS	183364-82-1
MW:	271.2 D

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CPPG

Item number: TGM-T10880-10mg

Description: CPPG is a potent antagonist of group II/III mGlu receptors. CPPG exhibits some selectivity (approximately 20 fold) for group III (IC50: 2.2 nM) over group II (IC50: 46.2 nM) mGlu receptors in the rat cerebral cortex. Target: Others. Smiles: C(C(O)=O)(N)(C1CC1)C2=CC=C(P(=O)(O)O)C=C2. References: Toms NJ,...

Keywords:	(RS)-CPPG
CAS	183364-82-1
MW:	271.21 D

From 125.00€ *

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