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Erlotinib
Erlotinib

Item number: Cay10483-250

Erlotinib is an EGFR inhibitor (Ki = 2.7 nM). It is greater than 1,000-fold selective for EGFR over Src and Abl at 0.1 µM. Erlotinib induces caspase-3 and -7 activity in NCI H358 non-small cell lung cancer (NSCLC) cells when used at a concentration of 1 µM. Erlotinib (25 mg/kg) reduces EGF-induced EGFR...
Keywords: NSC 718781, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine
Application: Tyrosine kinase inhibitor
CAS 183321-74-6
MW: 393.4 D
From 43.00€ *
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Erlotinib, Free Base (CP-358774, D07907, OSI-774, Ro 50-8231, RO508231, Tarceva, CAS 183321-74-6), >
Erlotinib, Free Base (CP-358774, D07907, OSI-774, Ro...

Item number: LC-E-4997_500mg

Soluble in DMSO at 100 mg/mL, soluble in ethanol at 10 mg/mL with warming, very poorly soluble in water, maximum solubility in plain water is estimated to be about 5-20 µM, buffers, serum, or other additives may increase or decrease the aqueous solubility
Keywords: NSC 718781, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine
Application: Tyrosine kinase inhibitor
CAS 183321-74-6
MW: 393,44 D
From 80.00€ *
Review