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Item number: Cay18113-500

YM-53601 is a squalene synthase inhibitor (IC50s = 79 and 90 nM in HepG2 cells and rat liver microsomes, respectively). It inhibits cholesterol biosynthesis in rats (ED50 = 32 mg/kg). YM-53601 dose-dependently reduces plasma triglyceride and non-HDL cholesterol levels in hamsters fed both normal and high-fat diets....

Keywords:	2-[(2E)-2-(1-azabicyclo[2.2.2]oct-3-ylidene)-2-fluoroethoxy]-9H-carbazole, monohydrochloride
Application:	Squalene synthase inhibitor
CAS	182959-33-7
MW:	372.9 D

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YM-53601

Item number: TGM-T26345-1mg

Description: YM-53601 is a potent squalene synthase (SQS) inhibitor that inhibits adipogenic biosynthesis and lipid secretion in rodents.YM-53601 is a cholesterol-lowering agent that inhibits farnesyl diphosphate farnesyltransferase 1 (FDFT1).YM-53601 exhibits potential antiviral activity and enhances...

Keywords:	YM53601 , YM 53601
Application:	Squalene synthase inhibitor
CAS	182959-33-7
MW:	372.86 D

From 153.00€ *

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