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Lorundrostat
Item number: Cay43548-1
Lorundrostat is an inhibitor of aldosterone synthase, also known as cytochrome P450 (CYP) 11B2 (CYP11B2, IC50 = 1.27 nM). It is selective for aldosterone synthase over CYP11B1 (IC50 = 475 nM). SMILES CC1=CC=C(C2=NC(N3CCN(CC(N[C@@H]4CC[C@H](CC4)NC(C)=O)=O)CC3)=NN=C2)C=C1 InChi Code...
| Keywords: | MLS-101, MT-4129, N-[trans-4-(acetylamino)cyclohexyl]-4-[5-(4-methylphenyl)-1,2,4-triazin-3-yl]-1-piperazineacetamide |
| Application: | Aldosterone synthase inhibitor |
| CAS | 1820940-17-7 |
| MW: | 451.58 D |
From 53.00€
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Lorundrostat
Item number: TGM-T62747-100mg
Description: Lorundrostat (MT-4129) is an aldosterone synthase inhibitor with antihypertensive activity that lowers systolic blood pressure. Target: Others. Smiles: CC(=O)N[C@H]1CC[C@@H](CC1)NC(=O)CN1CCN(CC1)c1nncc(n1)-c1ccc(C)cc1. References: Laffin LJ, et al. Aldosterone Synthase Inhibition With Lorundrostat for...
| Keywords: | MLS-101, MT 4129, MLS101, MLS 101, MT-4129, MT4129 |
| Application: | Targets steroid 11beta-monooxygenase / corticosterone 18-monooxygenase (CYP11B2) |
| CAS | 1820940-17-7 |
| MW: | 451.56 D |
From 52.00€
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