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Item number: TGM-T5417-100mg

Description: INCB057643 is a potent, selective and orally bioavailable BET inhibitor. Target: Apoptosis, Epigenetic Reader Domain. Smiles: CN1C(=O)C(C)(C)Oc2c1cc(cc2-c1cn(C)c(=O)c2[nH]ccc12)S(C)(=O)=O. References: Matthew C. Stubbs, et al. Abstract 5071: Preclinical characterization of the potent and selective BET...

Application:	BET family protein inhibitor
CAS	1820889-23-3
MW:	415.46 D

From 37.00€ *

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INCB 057643

Item number: Cay31456-1

INCB 057643 is a bromodomain and extra terminal domain (BET) family protein inhibitor. It inhibits binding of bromodomain-containing protein 2 (BRD2), BRD3, and BRD4 to an acetylated histone H4 peptide in vitro. INCB 057643 decreases Myc levels in, and inhibits proliferation of, acute myeloid leukemia (AML), diffuse...

Keywords:	8-(6,7-dihydro-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-2,2,4-trimethyl-6-(methylsulfonyl)-2H-1,4-benzoxazin-3(4H)-one
Application:	BET family protein inhibitor
CAS	1820889-23-3
MW:	415.5 D

From 85.00€ *

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