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KB-R7943 mesylate
Item number: TGM-T6144-100mg
Description: KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev), with an IC50 of 5.7±2.1 µM. Target: Na+/Ca2+ Exchanger, Autophagy. Smiles: CS(O)(=O)=O.NC(=N)SCCc1ccc(OCc2ccc(cc2)[N+]([O-])=O)cc1. References: Brustovetsky T , Brittain M K , Sheets P L , et al. KB-R7943, an...
| Keywords: | KB-R7943 |
| Application: | NCX1 inhibitor |
| CAS | 182004-65-5 |
| MW: | 427.5 D |
From 49.00€
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KB-R7943 (mesylate)
Item number: Cay16352-10
The Na+/Ca2+ exchanger (NCX) is a major regulator of intracellular calcium concentration that is largely expressed in cardiac sarcolemma (NCX1) but also in brain and skeletal muscle (NCX2). KB-R7943 is an isothiourea derivative that selectively inhibits the reverse mode of NCX1 (IC50 = 1.2-2.4 µM), preventing...
| Keywords: | 2-[4-[(4-nitrophenyl)methoxy]phenyl]ethyl ester carbamimidothioic acid, monomethanesulfonate |
| Application: | NCX1 inhibitor |
| CAS | 182004-65-5 |
| MW: | 427.5 D |
From 67.00€
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