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Item number: Cay21582-5

SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1, IC50 = 5.9 nM). It is selective for SRPK1 over a panel of 50 kinases at a concentration of 1 µM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1), an SRPK1 substrate, in PC3 cells (EC50 = 360 nM) and...

Keywords:	5-(4-pyridinyl)-N-[2-[4-(2-pyridinylmethyl)-1-piperazinyl]-5-(trifluoromethyl)phenyl]-2-furancarboxamide
Application:	SRPK1 inhibitor
CAS	1818389-84-2
MW:	507.5 D

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