2 products were found matching "1818314-88-3"!
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BMS 1166
Item number: Cay31441-5
BMS 1166 is an inhibitor of the protein-protein interaction between programmed cell death 1 (PD-1) and its ligand PD-L1 that has an IC50 value of 1.4 nM in a homologous time-resolved fluorescence (HTRF) assay. It increases the activation of Jurkat cells expressing PD-1 in co-culture with CHO cells expressing PD-L1...
| Keywords: | (4R)-1-[[5-chloro-2-[(3-cyanophenyl)methoxy]-4-[[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylphenyl]methoxy]phenyl]methyl... |
| Application: | PD-1/PD-L1 interaction inhibitor |
| CAS | 1818314-88-3 |
| MW: | 641.1 D |
From 100.00€
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BMS-1166
Item number: TGM-T5697-100mg
Description: BMS-1166 is a potent inhibitor of the PD-1/PD-L1 interaction. Target: PD-1/PD-L1. Smiles: Cc1c(COc2cc(OCc3cccc(c3)C#N)c(CN3C[C@H](O)C[C@@H]3C(O)=O)cc2Cl)cccc1-c1ccc2OCCOc2c1. References: Skalniak L , Zak K M , Guzik K , et al. Small-molecule inhibitors of PD-1/PD-L1 immune checkpoint alleviate the...
| Application: | PD-1/PD-L1 interaction inhibitor |
| CAS | 1818314-88-3 |
| MW: | 641.11 D |
From 65.00€
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