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Almotriptan (malate)
Almotriptan (malate)

Item number: Cay25646-5

Almotriptan is an agonist of the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D (IC50s = 12 and 13 nM, respectively, in a radioligand binding assay). It is selective for human 5-HT1B and 5-HT1D receptors over rat 5-HT1A and human 5-HT2A and 5-HT4 receptors (IC50s = 0.85, 25.1, and 140 µM, respectively)....
Keywords: PNU 180638E, 2-hydroxy-butanedioic acid, compd. with N,N-dimethyl-5-[(1-pyrrolidinylsulfonyl)methyl]-1H-indole-3-ethanamine
Application: 5-HT1B / 5-HT1D serotonin receptor agonist
CAS 181183-52-8
MW: 469.6 D
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Almotriptan Malate
Almotriptan Malate

Item number: TGM-T2317-100mg

Description: Almotriptan Malate (PNU180638), a selective 5-HT1B/1D receptor agonist, is used in the therapy of Migraine attacks in adults. Target: 5-HT Receptor. Smiles: c1c(cc2c(c1)[nH]cc2CCN(C)C)CS(=O)(=O)N1CCCC1.OC(=O)C(CC(=O)O)O. References: Dodick, D. (2003). A review of the clinical efficacy and tolerability...
Keywords: PNU180638, LAS 31416
CAS 181183-52-8
MW: 469.55 D
From 29.00€ *
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