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CHMFL-BMX-078
Item number: TGM-T4268-100mg
Description: CHMFL-BMX-078 is a highly potent and selective type II irreversible inhibitor of BMX kinase, with an IC50 of 11 nM. Target: BTK. Smiles: CNc1nc(Nc2ccc(C)c(NC(=O)C=C)c2)ncc1C(=O)Nc1cc(NC(=O)c2cc(OC)c(OC)c(OC)c2)ccc1C. References: Liang X, et al. Discovery of...
| Application: | Irreversible BMX inhibitor |
| CAS | 1808288-51-8 |
| MW: | 625.67 D |
From 63.00€
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CHMFL-BMX-078
Item number: Cay36828-10
CHMFL-BMX-078 is an irreversible inhibitor of bone marrow tyrosine kinase on chromosome X (BMX, IC50 = 11 nM). It selectively inhibits the growth of Ba/F3 cells expressing BMX over Ba/F3 cells expressing Abl, c-Kit, PDGFRalpha, or PDGFRbeta (GI50s = 0.016, 2.56, 2.01, 0.67, and 0.91 µM, respectively), as well as...
| Keywords: | 4-(methylamino)-2-[[4-methyl-3-[(1-oxo-2-propen-1-yl)amino]phenyl]amino]-N-[2-methyl-5-[(3,4,5-trimethoxybenzoyl)amino]phe... |
| Application: | Irreversible BMX inhibitor |
| CAS | 1808288-51-8 |
| MW: | 625.7 D |
From 122.00€
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