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Item number: Cay17079-1

BB-Cl-amidine is a pan inhibitor of peptidyl arginine deiminases (PADs) and a proteolysis-resistant derivative of Cl-amidine (Cay-10599). It irreversibly inhibits PAD1-4 (kinact/KI = 16,100, 4,100, 6,800, and 13,300 M-1min-1, respectively). BB-Cl-amidine (20 and 200 µM) inhibits the formation of neutrophil...

Keywords:	N-[(1S)-1-(1H-benzimidazol-2-yl)-4-[(2-chloro-1-iminoethyl)amino]butyl]-[1,1'-biphenyl]-4-carboxamide
Application:	PADI4 inhibitor
CAS	1802637-39-3
MW:	460 D

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