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NCT-501
Item number: Cay21162-5
NCT-501 is a potent, reversible, theophylline-based inhibitor of ALDH1A1 (IC50 = 40 nM for the human form). It is selective for ALDH1A1 over other ALDH isozymes as well as other dehydrogenases. Pharmacokinetic studies indicate that NCT-501 has high bioavailability when delivered intraperitoneally, with rapid phase I...
| Keywords: | 8-[[4-(cyclopropylcarbonyl)-1-piperazinyl]methyl]-3,7-dihydro-1,3-dimethyl-7-(3-methylbutyl)-1H-purine-2,6-dione |
| Application: | ALDH1A1 inhibitor |
| CAS | 1802088-50-1 |
| MW: | 416.5 D |
From 85.00€
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NCT-501
Item number: TGM-T6903-100mg
Description: NCT-501 is a potent and selective inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1) with an IC50 of 40 nM. Target: Dehydrogenase. Smiles: CC(C)CCn1c(CN2CCN(CC2)C(=O)C2CC2)nc2n(C)c(=O)n(C)c(=O)c12. References: Yang SM, et al. J Med Chem. 2015, 58(15), 5967-5978.
| Keywords: | NCT501 |
| Application: | ALDH1A1 inhibitor |
| CAS | 1802088-50-1 |
| MW: | 416.52 D |
From 39.00€
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