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OICR-9429
OICR-9429

Item number: Cay16095-1

WD-repeat protein 5 (WDR5) is a scaffold protein commonly involved in the formation of nucleosome-modifying protein complexes with histones. For example, WDR5 is a component of a mixed-lineage leukemia (MLL) methyltransferase complex that targets histone 3. WDR5 can also be a component of histone acetyltransferase...
Keywords: N-(4-(4-methylpiperazin-1-yl)-3'-(morpholinomethyl)-[1,1'-biphenyl]-3-yl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine-3-...
Application: WDR5 binding inhibitor
CAS 1801787-56-3
MW: 555.6 D
From 85.00€ *
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OICR-9429
OICR-9429

Item number: TGM-T6916-100mg

Description: OICR-9429 is a potent antagonist of the interaction that WDR5 effect with peptide regions of MLL and Histone 3. It reduces the viability of acute myeloid leukemia cells in vitro. Target: Histone Methyltransferase, JAK. Smiles: CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cccc(CN2CCOCC2)c1....
Keywords: OICR 9429
Application: WDR5 binding inhibitor
CAS 1801787-56-3
MW: 555.59 D
From 30.00€ *
Review