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Item number: Cay45050-1

A MEK1 inhibitor, selective for MEK1 over a panel of kinases panel at 10 µM, selectively reduces proliferation in a panel of cancer cell lines expressing mutant K-Ras or B-RAF (IC50s = 0.67-59.89 nM) over H1975 cells expressing wild-type K-Ras and B-Raf (IC50 = >1,000 nM), inhibits ERK phosphorylation in A375 cells...

Keywords:	HL 085, 4-fluoro-5-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)-6-benzothiazolecarboxamide
Application:	MEK1 inhibitor
CAS	1801756-06-8
MW:	491.25 D

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