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CA-4948
CA-4948

Item number: TGM-T9027-100mg

Description: CA-4948 (Emavusertib) is a potent IRAK4/FLT3 inhibtor. CA-4948 with anti-tumor activity. Target: IRAK, FLT. Smiles: Cc1cc(ccn1)-c1nc(co1)C(=O)Nc1cc2oc(nc2nc1N1CC[C@@H](O)C1)N1CCOCC1. References: Wiese MD, et al. Investigational IRAK-4 inhibitors for the treatment of rheumatoid arthritis. Expert Opin...
Keywords: Emavusertib
Application: Targets interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1] (IRAK4)
CAS 1801344-14-8
MW: 491.5 D
From 31.00€ *
Review
Emavusertib
Emavusertib

Item number: Cay36845-5

Emavusertib is an inhibitor of IL-1 receptor-associated kinase 4 (IRAK4, IC50 = 31.7 nM). It is selective for IRAK4 over FMS-related tyrosine kinase 3 (FLT3), cyclin-dependent kinase 2 (Cdk2), Aurora A kinase, glycogen synthase kinase 3beta (GSK3beta), and muscle-associated receptor tyrosine kinase (MUSK) at 1 µM....
Keywords: CA-4948,...
Application: IRAK4 inhibitor
CAS 1801344-14-8
MW: 491.5 D
From 67.00€ *
Review