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GSK180
GSK180

Item number: TGM-T15426-1mL

Description: GSK180 is a selective competitive inhibitor of kynurenine 3-monooxygenase (KMO, IC50: ~6 nM), an enzyme involved in tryptophan metabolism. Target: Hydroxylase. Smiles: OC(=O)CCn1c2cc(Cl)c(Cl)cc2oc1=O. References: Mole DJ, et al. Kynurenine-3-monooxygenase inhibition prevents multiple organ failure in...
CAS 1799725-26-0
MW: 276.07 D
From 81.00€ *
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GSK180
GSK180

Item number: Cay19217-1

An inhibitor of kynurenine 3-monooxygenase (IC50 = 6.3 nM), selective for human over P. fluorescens kynurenine 3-monooxygenase (IC50 = 500 nM), increases circulating levels of kynurenine and kynurenic acid in mice at 27 mg/kg, protects against secondary acute lung injury and renal injury in a rat model of...
Keywords: 5,6-dichloro-2-oxo-3(2H)-benzoxazolepropanoic acid
Application: Kynurenine 3-monooxygenase inhibitor
CAS 1799725-26-0
MW: 276.1 D
From 55.00€ *
Review